SimpliMax

Amnion Membrane Allograft

What is SimpliMax?

SimpliMax is a dehydrated, dual-layer amnion membrane allograft. The allograft is derived from human placental membrane collected from a consenting donor and processed aseptically. It is terminally sterilized to achieve a sterility assurance level (SAL) of 1 x 10-6 utilizing gamma irradiation. SimpliMax is packaged as a sterile product in sealed, single-use pouches. SimpliMax is processed in compliance with all current Good Tissue Practices as mandated by the United States Food and Drug Administration and the American Association of Tissue Banks.

Only tissues from donors meeting the prescribed criteria are processed for manufacturing of SimpliMax.

Infectious Disease Screened In Blood Specimens Of Donor

  • HIV-1/2 antibody
  • Hepatitis B surface antigen
  • Hepatitis B core antibody (Total)
  • Hepatitis C antibody
  • HTLV I/II
  • HIV (NAT)
  • HBV (NAT)
  • HCV (NAT)
  • Malaria
  • Syphilis
  • WNV (NAT)

Benefits of SimpliMax

  • Placental tissue allograft composed of dual layer amnion
  • Non-side specific orientation for application
  • Thicker membrane for deep wounds or exposed anatomy that can be easily positioned or repositioned for improved conformity
  • Enhanced tensile strength, adheres well, and easy to apply
  • Can be used in a hydrated or dehydrated state
  • Retains important major structural proteins and ECM biochemicals that are naturally present in placental tissue

Why SimpliMax?

SimpliMax is intended for the repair, reconstruction, replacement, or supplementation of a patient's injured tissue.

Potential SimpliMax Applications

  • Podiatry/Vascular
  • Wound Management
  • Orthopaedic Surgery
  • Other Surgical Scenarios

Potential SimpliMax Benefits

  • Flexible
  • Protective Covering
  • Non-Steroidal
  • All-Natural

Known Presence Of Growth Factors & Cytokines In The Extracellular Matrix Of Human Placental Tissue And Their Functions:

Growth Factors and CytokinesNative FunctionSimpliMax
IL-1ra, IL-4, IL-6, IL-10Anti-Inflammatory✓
VEGFAngiogenic✓
bFGFAngiogenic✓
TFG-BetaAngiogenic✓
PDGFAngiogenic✓
EGFAngiogenic✓
IGF-1Cell Proliferation and remodeling✓
KGFCell Proliferation and remodeling✓
MIPAnti-Bacterial✓

Why Amniotic Membrane?

Human amniotic membrane forms the innermost layer of placenta tissue.

The avascular membrane acts as a protective barrier for the developing fetus. Its properties provide a wide variety of potential benefits in regenerative medicine.

Dual Layer

Protective Covering

The membrane sheet provides a protective covering that may aid in wound management.

Simple Application

Immunogenicity

The amniotic membrane has unique non-immunological properties.

Surgical Barrier

Scaffold

The extracellular matrix acts as a scaffolding and potentiates the migration and adhesion of resident cells.

Easy Placement

Growth Factors

Natural cytokines in the membrane.

Ordering Information

SimpliMax Amnion Membrane Allograft Ordering Information

SizeProduct ID
2cm x 2cmSM-0202
2cm x 3cmSM-0203
4cm x 4cmSM-0404
4cm x 8cmSM-0408

To order, call (407) 212-1314 or email orders@curamedicalsolutions.com.

No statements or implied treatments on this advertisement have been evaluated or approved by the FDA. This advertisement contains no medical advice. All statements and opinions provided by this advertisement are provided for educational and informational purposes only and is not intended to diagnose nor treat any conditions.

To order, call (407) 212-1314

Or email orders@curamedicalsolutions.com.